Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Left ventricular non-compaction in identical twins with thalassaemia and cardiac iron overload Luckie M; Irwin B; Nair S; Greenwood J; Khattar REur J Echocardiogr 2009[Jun]; 10 (4): 509-12Cardiac disease in patients with transfusion-dependent beta-thalassaemia major is well described. Cardiac manifestations may include left ventricular wall thickening and both systolic and diastolic dysfunctions. We describe a group of family members, including a pair of identical twins, each of whom suffered from thalassaemia major requiring multiple transfusions. Cardiac magnetic resonance demonstrated myocardial iron overload, and impairment of systolic function. Echocardiography confirmed both significant left ventricular systolic and diastolic impairment, along with features consistent with left ventricular non-compaction. This finding has not been noted in association with thalassaemia-related cardiac disease before. We then review the cardiac manifestations which occur in association with thalassaemia major.|Deferoxamine/therapeutic use[MESH]|Diseases in Twins/*diagnostic imaging[MESH]|Echocardiography[MESH]|Female[MESH]|Ferritins/blood[MESH]|Genetic Predisposition to Disease[MESH]|Heart Diseases/*diagnosis/etiology[MESH]|Humans[MESH]|Iron Chelating Agents/therapeutic use[MESH]|Iron Overload/*diagnosis/drug therapy/etiology[MESH]|Magnetic Resonance Imaging[MESH]|Male[MESH]|Myocardium/pathology[MESH]|Siblings[MESH]|Transfusion Reaction[MESH]|Ventricular Dysfunction, Left/*diagnostic imaging[MESH]|Young Adult[MESH]|beta-Thalassemia/*complications/diagnostic imaging/therapy[MESH] |
