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How to study lipidomes Seppanen-Laakso T; Oresic MJ Mol Endocrinol 2009[Mar]; 42 (3): 185-90Lipidome is loosely defined as the entire spectrum of lipids in a biological system. Given the modern lipidomics platforms for the first time empower us with the ability to obtain a snapshot of complete cellular/organismal lipidome, many surprises and discoveries are likely awaiting us in the area of lipids as related to cellular/organismal physiology. The lipidomics approaches can be applied both as the phenotyping platform and for the hypothesis-driven research aiming to elucidate, e.g., a specific pathway or gene function. Modern lipidomics methods combine the latest mass spectrometry technology and bioinformatics methods with traditional methods such as for sample preparation and lipid extraction.|*Lipid Metabolism/genetics/physiology[MESH]|Animals[MESH]|Biology/*methods[MESH]|Computational Biology[MESH]|Humans[MESH]|Lipids/*analysis/*chemistry/physiology[MESH]|Mass Spectrometry[MESH] |
