suck pdf from google scholar
unlimited free pdf from europmc19041366    free
PDF from PMC    free
html from PMC    free
PDF vom PMID19041366  :  Publisher
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text


  • DeepDyve
  • Pubget Overpricing


  • lüll
  • Hungry for life: How the arcuate nucleus and neuropeptide Y may play a critical role in mediating the benefits of calorie restriction
  • Minor RK; Chang JW; de Cabo R
  • Mol Cell Endocrinol 2009[Feb]; 299 (1): 79-88
  • Laboratory studies consistently demonstrate extended lifespan in animals on calorie restriction (CR), where total caloric intake is reduced by 10-40% but adequate nutrition is otherwise maintained. CR has been further shown to delay the onset and severity of chronic diseases associated with aging such as cancer, and to extend the functional health span of important faculties like cognition. Less understood are the underlying mechanisms through which CR might act to induce such alterations. One theory postulates that CR's beneficial effects are intimately tied to the neuroendocrine response to low energy availability, of which the arcuate nucleus in the hypothalamus plays a pivotal role. Neuropeptide Y (NPY), a neurotransmitter in the front line of the arcuate response to low energy availability, is the primary hunger signal affected by CR and therefore may be a critical mechanism for lifespan extension.
  • |*Caloric Restriction[MESH]
  • |Aging/physiology[MESH]
  • |Animals[MESH]
  • |Arcuate Nucleus of Hypothalamus/*physiology[MESH]
  • |Humans[MESH]
  • |Hunger/*physiology[MESH]
  • |Longevity/*physiology[MESH]
  • |Models, Biological[MESH]
  • |Neuropeptide Y/*physiology[MESH]





  • *{{pmid19041366}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=19041366 Hungry for life: How the arcuate nucleus and neuropeptide Y may play a critical role in mediating the benefits of calorie restriction ]</b> Mol Cell Endocrinol 2009; 299(1) ; 79-88 Minor RK; Chang JW; de Cabo R

        *19041366*

    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    Mol Cell Endocrinol

    79 1.299 2009