Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Polymyxins: a review of the current status including recent developments Kwa AL; Tam VH; Falagas MEAnn Acad Med Singap 2008[Oct]; 37 (10): 870-83INTRODUCTION: Polymyxins have become the drug of choice for treatment of multidrug-resistant gram-negative bacilli infections in Singapore, simply because these pathogens are only susceptible to either aminoglycosides and polymyxins, or polymyxins only. Furthermore, there is no new antibiotic in the pipeline that targets these difficult-to-treat infections. MATERIALS AND METHODS: All published literatures (up to end of February 2008) regarding polymyxins are included for review. RESULTS: This review serves to give a summary of polymyxins from the current available literature, highlighting relevant clinical studies and information that help to guide informed prescription of polymyxins, should the need arise. CONCLUSIONS: However, there are substantial information gaps that needed to be filled urgently, to preserve the clinical utility of this very last line of antibiotic.|Anti-Bacterial Agents/*pharmacology/therapeutic use[MESH]|Drug Resistance, Multiple, Bacterial[MESH]|Gram-Negative Bacteria/*drug effects[MESH]|Gram-Negative Bacterial Infections/*drug therapy/microbiology[MESH]|Humans[MESH]|Microbial Sensitivity Tests[MESH]|Polymyxins/*pharmacology/therapeutic use[MESH]|Singapore[MESH] |