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A review of independent component analysis application to microarray gene expression data Kong W; Vanderburg CR; Gunshin H; Rogers JT; Huang XBiotechniques 2008[Nov]; 45 (5): 501-20Independent component analysis (ICA) methods have received growing attention as effective data-mining tools for microarray gene expression data. As a technique of higher-order statistical analysis, ICA is capable of extracting biologically relevant gene expression features from microarray data. Herein we have reviewed the latest applications and the extended algorithms of ICA in gene clustering, classification, and identification. The theoretical frameworks of ICA have been described to further illustrate its feature extraction function in microarray data analysis.|*Gene Expression[MESH]|*Principal Component Analysis[MESH]|Algorithms[MESH]|Cluster Analysis[MESH]|Humans[MESH]|Least-Squares Analysis[MESH]|Neoplasms/*classification/genetics[MESH]|Oligonucleotide Array Sequence Analysis/*methods[MESH]|Pattern Recognition, Automated/*methods[MESH]|Signal Transduction[MESH] |
