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lüll Epigenetics in the nervous system Jiang Y; Langley B; Lubin FD; Renthal W; Wood MA; Yasui DH; Kumar A; Nestler EJ; Akbarian S; Beckel-Mitchener ACJ Neurosci 2008[Nov]; 28 (46): 11753-9It is becoming increasingly clear that epigenetic modifications are critical factors in the regulation of gene expression. With regard to the nervous system, epigenetic alterations play a role in a diverse set of processes and have been implicated in a variety of disorders. Gaining a more complete understanding of the essential components and underlying mechanisms involved in epigenetic regulation could lead to novel treatments for a number of neurological and psychiatric conditions.|Animals[MESH]|Brain Diseases/*genetics/*metabolism/physiopathology[MESH]|Chromatin/genetics/metabolism[MESH]|DNA Methylation/genetics[MESH]|Epigenesis, Genetic/*genetics[MESH]|Gene Expression Regulation/*genetics[MESH]|Genetic Predisposition to Disease/*genetics[MESH]|Histone Deacetylase Inhibitors[MESH]|Histone Deacetylases/metabolism[MESH]|Histones/genetics/metabolism[MESH]|Humans[MESH]|Nervous System/*metabolism[MESH] |