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Engineered polymers for advanced drug delivery Kim S; Kim JH; Jeon O; Kwon IC; Park KEur J Pharm Biopharm 2009[Mar]; 71 (3): 420-30Engineered polymers have been utilized for developing advanced drug delivery systems. The development of such polymers has caused advances in polymer chemistry, which, in turn, has resulted in smart polymers that can respond to changes in environmental condition such as temperature, pH, and biomolecules. The responses vary widely from swelling/deswelling to degradation. Drug-polymer conjugates and drug-containing nano/micro-particles have been used for drug targeting. Engineered polymers and polymeric systems have also been used in new areas, such as molecular imaging as well as in nanotechnology. This review examines the engineered polymers that have been used as traditional drug delivery systems and as more recent applications in nanotechnology.|*Drug Delivery Systems[MESH]|Animals[MESH]|Chemistry, Pharmaceutical[MESH]|Delayed-Action Preparations[MESH]|Drug Carriers/*chemistry[MESH]|Humans[MESH]|Hydrogen-Ion Concentration[MESH]|Microspheres[MESH]|Nanoparticles/administration & dosage[MESH]|Nanotechnology[MESH]|Polymers/*chemistry[MESH]|Temperature[MESH] |
