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lüll Ischemic preconditioning of the liver: a few perspectives from the bench to bedside translation Desai KK; Dikdan GS; Shareef A; Koneru BLiver Transpl 2008[Nov]; 14 (11): 1569-77Utilization of ischemic preconditioning to ameliorate ischemia/reperfusion injury has been extensively studied in various organs and species for the past two decades. While hepatic ischemic preconditioning in animals has been largely beneficial, translational efforts in the two clinical contexts--liver resection and decreased donor liver transplantation--have yielded mixed results. This review is intended to critically examine the translational data and identify some potential reasons for the disparate clinical results, and highlight some issues for further studies.|*Ischemic Preconditioning[MESH]|Aged[MESH]|Animals[MESH]|Brain Death[MESH]|Clinical Trials as Topic[MESH]|Disease Models, Animal[MESH]|Humans[MESH]|Liver Function Tests[MESH]|Liver Transplantation/*methods[MESH]|Liver/surgery[MESH]|Middle Aged[MESH]|Reperfusion Injury[MESH]|Time Factors[MESH] |