Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Practical aspects of imputation-driven meta-analysis of genome-wide association studies de Bakker PI; Ferreira MA; Jia X; Neale BM; Raychaudhuri S; Voight BFHum Mol Genet 2008[Oct]; 17 (R2): R122-8Motivated by the overwhelming success of genome-wide association studies, droves of researchers are working vigorously to exchange and to combine genetic data to expediently discover genetic risk factors for common human traits. The primary tools that fuel these new efforts are imputation, allowing researchers who have collected data on a diversity of genotype platforms to share data in a uniformly exchangeable format, and meta-analysis for pooling statistical support for a genotype-phenotype association. As many groups are forming collaborations to engage in these efforts, this review collects a series of guidelines, practical detail and learned experiences from a variety of individuals who have contributed to the subject.|*Meta-Analysis as Topic[MESH]|*Polymorphism, Single Nucleotide[MESH]|Data Interpretation, Statistical[MESH]|Genetic Predisposition to Disease[MESH]|Genome, Human/genetics[MESH]|Genome-Wide Association Study/*methods/standards[MESH]|Humans[MESH]|Phenotype[MESH] |
