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lüll How we have learned about the complexity of physiology, pathobiology and pharmacology of bile acids and biliary secretion Marin JJWorld J Gastroenterol 2008[Oct]; 14 (37): 5617-9During the last decades the concept of bile secretion as merely a way to add detergent components to the intestinal mixture to facilitate fat digestion/absorption and to eliminate side products of heme metabolism has evolved considerably. In the series of mini-reviews that the World Journal of Gastroenterology is to publish in its section of "Highlight Topics", we will intend to give a brief but updated overview of our knowledge in this field. This introductory letter is intended to thank all scientists who have contributed to the development of this area of knowledge in gastroenterology.|Animals[MESH]|Bile Acids and Salts/*metabolism/therapeutic use[MESH]|Bile/*metabolism[MESH]|Biliary Tract Diseases/metabolism/*physiopathology[MESH]|Biliary Tract/*metabolism/physiopathology[MESH]|Carrier Proteins/metabolism[MESH]|Enterohepatic Circulation[MESH]|Humans[MESH]|Intestinal Mucosa/metabolism[MESH]|Liver/metabolism[MESH]|Membrane Glycoproteins/metabolism[MESH] |