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lüll T-wave alternans testing for ventricular arrhythmias Narayan SMProg Cardiovasc Dis 2008[Sep]; 51 (2): 118-27T-wave alterans (TWA) measures alternate-beat fluctuations in the ECG T-wave, and has been used to predict the risk for life-threatening ventricular arrhythmias in various clinical populations. This work reviews the traditional literature linking repolarization alternans in cellular and tissue-level studies, with clinical studies that TWA can successfully add to existing clinical risk factors in predicting ventricular arrhythmias. We conclude by providing an evidence-based framework integrating TWA with other risk factors to stratify risk for sudden cardiac arrest.|*Electrocardiography[MESH]|Action Potentials[MESH]|Arrhythmias, Cardiac/complications/*diagnosis/physiopathology[MESH]|Coronary Disease/complications/*diagnosis/physiopathology[MESH]|Death, Sudden, Cardiac/*etiology[MESH]|Evidence-Based Medicine[MESH]|Heart Rate[MESH]|Heart Ventricles/physiopathology[MESH]|Humans[MESH]|Predictive Value of Tests[MESH]|Risk Assessment[MESH]|Risk Factors[MESH]|Signal Processing, Computer-Assisted[MESH]|Time Factors[MESH]|Ventricular Dysfunction, Left/complications/*diagnosis/physiopathology[MESH] |