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lüll Vertebral osteomyelitis with spinal epidural abscess in two patients with Bacteroides fragilis bacteraemia de Goeij S; Nisolle JF; Glupczynski Y; Delgrange E; Delaere BActa Clin Belg 2008[May]; 63 (3): 193-6We report 2 cases of vertebral osteomyelitis and contiguous epidural abscess due to Bacteroides fragilis with no concomitant or past intra-abdominal infection. Decompressive surgery with laminectomy was required for both patients due to the occurrence of neurologic deficits. Clinical recovery was achieved after 8 weeks of antibiotic therapy. It included 3 weeks of intravenous therapy with clindamycin followed by an oral regimen of clindamycin for 1 patient and oral metronidazole for the other. In both cases, magnetic resonance imaging (MRI) has proved to be essential for diagnostic. The primary source of infection remained unknown despite careful investigations.|*Lumbar Vertebrae[MESH]|*Thoracic Vertebrae[MESH]|Aged[MESH]|Aged, 80 and over[MESH]|Bacteremia/diagnosis/*etiology/microbiology[MESH]|Bacteroides fragilis/genetics/*isolation & purification[MESH]|DNA, Bacterial/analysis[MESH]|Diagnosis, Differential[MESH]|Epidural Abscess/diagnosis/*etiology/microbiology[MESH]|Humans[MESH]|Male[MESH]|Osteomyelitis/complications/diagnosis/*microbiology[MESH]|Polymerase Chain Reaction[MESH]|Spinal Diseases/complications/diagnosis/*microbiology[MESH]|Tomography, X-Ray Computed[MESH] |