Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Anticonvulsants to treat idiopathic restless legs syndrome: systematic review Conti CF; Oliveira MM; Valbuza JS; Prado LB; Carvalho LB; Prado GFArq Neuropsiquiatr 2008[Jun]; 66 (2B): 431-5BACKGROUND: Restless legs syndrome (RLS) is a sensory motor disorder characterized by a distressing urge to move the legs and sometimes also other parts of the body usually accompanied by a marked sense of discomfort or pain in the leg or other affected body part. Many treatments have been used to minimize the discomfort of the disease, among them the anticonvulsant therapy. AIM: This review aims to evaluate the efficacy and safety of anticonvulsant treatment for idiopathic RLS. METHOD: Systematic review of randomized or quasi-randomized, double blind trials on anticonvulsant treatment for RLS. OUTCOMES: relief of RLS symptoms, subjective and objective sleep quality, quality of life, and adverse events associated with the treatments. RESULTS: A total of 231 patients were randomized in three cross over studies and one parallel study. Three studies with carbamazepine, one with sodium valproate, and one with gabapentin, and they were very heterogeneous so we could not perform a meta-analysis. CONCLUSIONS: There is no scientific evidence on RLS treatment with anticonvulsants for clinical practice.|Amines/therapeutic use[MESH]|Anticonvulsants/adverse effects/*therapeutic use[MESH]|Carbamazepine/therapeutic use[MESH]|Cyclohexanecarboxylic Acids/therapeutic use[MESH]|Evidence-Based Medicine[MESH]|Gabapentin[MESH]|Humans[MESH]|Restless Legs Syndrome/*drug therapy[MESH]|Treatment Outcome[MESH]|Valproic Acid/therapeutic use[MESH]|gamma-Aminobutyric Acid/therapeutic use[MESH] |
