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lüll Malignancy after solid organ transplantation: an overview Zafar SY; Howell DN; Gockerman JPOncologist 2008[Jul]; 13 (7): 769-78With improving survival following solid organ transplantation, clinicians must be aware of post-transplant complications. One increasingly frequent complication is the development of malignancy after transplantation. The most common malignancies encountered in the post-solid organ transplant setting are nonmelanoma skin cancers, post-transplant lymphoproliferative disorders, and Kaposi's sarcoma (KS). The pathogenesis of these tumors is likely related to the immunosuppressive drugs used post-transplantation and subsequent viral infection. Treatment involves modification of the immunosuppressive drug regimen, resection of localized disease, and chemotherapy. We present the second reported case of a patient with lung transplantation who developed KS in the lung graft.|Humans[MESH]|Immunocompromised Host/*immunology[MESH]|Lung Neoplasms/etiology/prevention & control/therapy[MESH]|Lymphoproliferative Disorders/etiology/prevention & control/therapy[MESH]|Male[MESH]|Middle Aged[MESH]|Neoplasms/*etiology/prevention & control/therapy[MESH]|Organ Transplantation/*adverse effects[MESH]|Sarcoma, Kaposi/etiology/prevention & control/therapy[MESH]|Skin Neoplasms/etiology/prevention & control/therapy[MESH] |