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lüll Radiologic and clinical findings of Behcet disease: comprehensive review of multisystemic involvement Chae EJ; Do KH; Seo JB; Park SH; Kang JW; Jang YM; Lee JS; Song JW; Song KS; Lee JH; Kim AY; Lim THRadiographics 2008[Sep]; 28 (5): e31Behcet disease is a chronic, relapsing, systemic disorder of unknown etiology, characterized by recurrent oral and genital ulcers, uveitis, and other clinical manifestations in multiple organ systems. Although the diagnosis is made on the basis of the combination of typical clinical symptoms, radiologic findings of Behcet disease show characteristic features of its involvement in the gastrointestinal, neurologic, cardiovascular, and thoracic organ systems. In the gastrointestinal tract, Behcet disease may produce various types of ulcers in the esophagus, stomach, and small and large intestines, as well as deeply penetrating ulcerations in the ileocecal region, with frequently accompanying enteric fistulas. Neurologic involvement includes typical and atypical parenchymal neurobehcet disease, dural sinus thrombosis, cerebral arterial aneurysm, occlusion, dissection, and meningitis. Vascular involvement is divided into three subsets including venous occlusion, arterial occlusion, and arterial aneurysm. Cardiac manifestations include intracardiac thrombus, endomyocardial fibrosis, periaortic pseudoaneurysm, and rupture of the sinus of Valsalva. Manifestations of Behcet disease in the thorax include pulmonary arterial aneurysm, pulmonary arterial thromboembolism, thrombosis in the superior vena cava, pulmonary infarction, hemorrhage, and vasculitis of the pleura and pericardium. These various manifestations of Behcet disease respond to steroid treatment; however, one of the characteristics of Behcet disease is the high rate of complications and recurrence after surgery. Familiarity with its various radiologic and clinical characteristics is essential in making an accurate early diagnosis and for prompt treatment of patients with Behcet disease.|Adult[MESH]|Aged[MESH]|Behcet Syndrome/*diagnostic imaging/*therapy[MESH]|Female[MESH]|Humans[MESH]|Male[MESH]|Middle Aged[MESH]|Multiple Organ Failure/*diagnostic imaging/*therapy[MESH]|Radiography[MESH]|Young Adult[MESH] |