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lüll A 50-year-old woman addicted to heroin: review of treatment of heroin addiction O'Brien CPJAMA 2008[Jul]; 300 (3): 314-21Heroin addiction is a complicated medical and psychiatric issue, with well-established as well as newer modes of treatment. The case of Ms W, a 50-year-old woman with a long history of opiate addiction who has been treated successfully with methadone for 9 years and who now would like to consider newer alternatives, illustrates the complex issues of heroin addiction. The treatment of heroin addiction as a chronic disease is reviewed, including social, medical, and cultural issues and pharmacologic treatment with methadone and the more experimental medication options of buprenorphine and naltrexone.|Buprenorphine/therapeutic use[MESH]|Drug Therapy, Combination[MESH]|Female[MESH]|Heroin Dependence/epidemiology/*rehabilitation[MESH]|History, 19th Century[MESH]|History, 20th Century[MESH]|Humans[MESH]|Methadone/history/*therapeutic use[MESH]|Middle Aged[MESH]|Naltrexone/therapeutic use[MESH]|Narcotic Antagonists/*therapeutic use[MESH]|Narcotics/history/*therapeutic use[MESH]|Opioid-Related Disorders/history[MESH]|Recurrence[MESH]|Self-Help Groups[MESH]|United States/epidemiology[MESH] |