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Roles of TRAF molecules in B lymphocyte function Xie P; Kraus ZJ; Stunz LL; Bishop GACytokine Growth Factor Rev 2008[Jun]; 19 (3-4): 199-207Tumor necrosis factor receptor associated factors (TRAFs) play a variety of interesting and important roles in the regulation of B lymphocyte function. They act both as cytoplasmic regulatory molecules, and as signal transducers for receptors involved in both innate and adaptive humoral immune responses. In this brief review, we highlight the current state of knowledge of the diverse roles of TRAF molecules in the functions of B lymphocytes.|Animals[MESH]|B-Cell Activation Factor Receptor/metabolism[MESH]|B-Lymphocytes/*immunology[MESH]|Humans[MESH]|Ki-1 Antigen/metabolism[MESH]|Mice[MESH]|Receptors, Tumor Necrosis Factor/metabolism[MESH]|Toll-Like Receptors/metabolism[MESH]|Tumor Necrosis Factor Ligand Superfamily Member 13/metabolism[MESH]|Tumor Necrosis Factor Receptor Superfamily, Member 7/metabolism[MESH]|Tumor Necrosis Factor Receptor-Associated Peptides and Proteins/*physiology[MESH]|Viral Matrix Proteins/metabolism[MESH] |
