Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Molecular structure of purinergic P2X receptors and their expression in the hypothalamus and pituitary Zemkova H; Balik A; Jindrichova M; Vavra VPhysiol Res 2008[]; 57 Suppl 3 (ä): S23-S38Purinergic P2X receptors represent a novel structural type of ligand-gated ion channels activated by extracellular ATP. So far, seven P2X receptor subunits have been found in excitable as well as non-excitable tissues. Little is known about their structure, mechanism of channel opening, localization, and role in the central nervous system. The aim of this work is to summarize recent investigations and describe our contribution to elucidating the structure of the ATP binding site and transmembrane domains of the P2X receptor, we also discuss the expression and physiological roles played by the ATP and P2X receptors in the anterior pituitary and hypothalamus.|Adenosine Triphosphate/metabolism[MESH]|Animals[MESH]|Gonadotrophs/metabolism[MESH]|Humans[MESH]|Hypothalamus/*metabolism[MESH]|Ivermectin/chemistry/pharmacology[MESH]|Models, Molecular[MESH]|Neuroglia/metabolism[MESH]|Neurons/metabolism[MESH]|Pituitary Gland/*metabolism[MESH]|Protein Binding[MESH]|Protein Structure, Quaternary[MESH]|Protein Structure, Secondary[MESH]|Protein Structure, Tertiary[MESH]|Receptors, Purinergic P2/*chemistry/drug effects/*metabolism[MESH] |