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Tissue microarray: a simple technology that has revolutionized research in pathology Avninder S; Ylaya K; Hewitt SMJ Postgrad Med 2008[Apr]; 54 (2): 158-62Tissue microarray (TMA) technology is a high-throughput research tool, which has greatly facilitated and accelerated tissue analyses by in-situ technologies. TMAs are amenable to every research method that can be applied on the standard whole sections at enhanced speed. It plays a central role in target verification of results from cDNA arrays, expression profiling of tumors and tissues, and is proving to be a powerful platform for proteomic research. In this review article, primarily meant for students of pathology and oncology, we briefly discuss its basic methodology, applications and merits and limitations.|Biomarkers, Tumor/genetics[MESH]|Cytological Techniques/*methods/trends[MESH]|Humans[MESH]|Immunohistochemistry/methods/trends[MESH]|Molecular Diagnostic Techniques[MESH]|Neoplasms/*genetics/pathology[MESH]|Oligonucleotide Array Sequence Analysis/*methods[MESH]|Prognosis[MESH]|Quality Control[MESH]|Tissue Array Analysis/*methods/trends[MESH] |
