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  lüll Pathogenesis of methicillin-resistant Staphylococcus aureus infection Gordon RJ; Lowy FDClin Infect Dis  2008[Jun]; 46 Suppl 5 (Suppl 5): S350-9Staphylococcus aureus is a versatile pathogen capable of causing a wide range of  human diseases. However, the role of different virulence factors in the  development of staphylococcal infections remains incompletely understood. Some  clonal types are well equipped to cause disease across the globe, whereas others  are facile at causing disease among community members. In this review, general  aspects of staphylococcal pathogenesis are addressed, with emphasis on  methicillin-resistant strains. Although methicillin-resistant S. aureus (MRSA)  strains are not necessarily more virulent than methicillin-sensitive S. aureus  strains, some MRSA strains contain factors or genetic backgrounds that may  enhance their virulence or may enable them to cause particular clinical  syndromes. We examine these pathogenic factors.|*Methicillin Resistance[MESH]|Humans[MESH]|Staphylococcal Infections/epidemiology/microbiology/*pathology/*physiopathology[MESH]|Staphylococcus aureus/*drug effects/genetics/*physiology[MESH]|Virulence[MESH]|Virulence Factors/*genetics/*physiology[MESH] |