Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Hyperphosphatemia of chronic kidney disease Hruska KA; Mathew S; Lund R; Qiu P; Pratt RKidney Int 2008[Jul]; 74 (2): 148-57Observational studies have determined hyperphosphatemia to be a cardiovascular risk factor in chronic kidney disease. Mechanistic studies have elucidated that hyperphosphatemia is a direct stimulus to vascular calcification, which is one cause of morbid cardiovascular events contributing to the excess mortality of chronic kidney disease. This review describes the pathobiology of hyperphosphatemia that develops as a consequence of positive phosphate balance in chronic kidney disease and the mechanisms by which hyperphosphatemia acts on neointimal vascular cells that are stimulated to mineralize in chronic kidney disease. The characterization of hyperphosphatemia of chronic kidney disease as a distinct syndrome in clinical medicine with unique disordered skeletal remodeling, heterotopic mineralization and cardiovascular morbidity is presented.|Calcinosis/*etiology/metabolism/mortality[MESH]|Cardiovascular Diseases/*etiology/metabolism/mortality[MESH]|Chronic Disease[MESH]|Chronic Kidney Disease-Mineral and Bone Disorder/etiology/metabolism[MESH]|Humans[MESH]|Hyperphosphatemia/complications/*metabolism/mortality[MESH]|Kidney Diseases/complications/*metabolism/mortality[MESH]|Osteoporosis/etiology/metabolism[MESH]|Phosphates/metabolism[MESH]|Syndrome[MESH] |
