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Longitudinal imaging in dementia Scahill RI; Fox NCBr J Radiol 2007[Dec]; 80 Spec No 2 (ä): S92-8Dementia represents one of the major public health problems facing ageing populations, with 20% of those over 80 years of age suffering from this disorder. The advent of therapeutic agents has brought about an increasing demand for a more accurate and earlier diagnosis, and the value of neuroimaging in improving the diagnostic process is becoming widely accepted. Neuroimaging assessments may add weight to a diagnosis of neurodegeneration as opposed to healthy ageing, improve the differential diagnosis, aid in the prediction of conversion to dementia in individuals at a higher risk of developing the disorder, track disease progression and provide an outcome measure for assessment of drug efficacy.|Alzheimer Disease/pathology[MESH]|Atrophy/pathology[MESH]|Brain/pathology[MESH]|Dementia/*pathology[MESH]|Disease Progression[MESH]|Humans[MESH]|Image Interpretation, Computer-Assisted/methods[MESH]|Longitudinal Studies[MESH]|Magnetic Resonance Imaging/methods[MESH] |
