Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Tumor escape mechanism governed by myeloid-derived suppressor cells Nagaraj S; Gabrilovich DICancer Res 2008[Apr]; 68 (8): 2561-3T-cell nonresponsiveness is a critical factor in immune escape and myeloid-derived suppressor cells play a major role in organizing this phenomenon. Recent findings indicate that myeloid-derived suppressor cells can induce antigen-specific CD8(+) T-cell tolerance through a posttranslation mechanism which involves modification (nitration) of CD8 and the T-cell receptor itself on the T-cell surface. Elucidation of this mechanism of T-cell tolerance offers new opportunities for therapeutic corrections of immune escape in cancer.|*Immune Tolerance[MESH]|*Immunosuppression Therapy[MESH]|CD8-Positive T-Lymphocytes/*immunology[MESH]|Humans[MESH]|Major Histocompatibility Complex[MESH]|Models, Immunological[MESH]|Neoplasms/*immunology/prevention & control[MESH]|Reactive Oxygen Species/immunology[MESH] |