Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Linking kinetochore-microtubule binding to the spindle checkpoint Burke DJ; Stukenberg PTDev Cell 2008[Apr]; 14 (4): 474-9The spindle checkpoint blocks cell-cycle progression until chromosomes are properly attached to the mitotic spindle. Popular models propose that checkpoint proteins associate with kinetochores to produce a "wait anaphase" signal that inhibits anaphase. Recent data suggest that a two-state switch results from using the same kinetochore proteins to bind microtubules and checkpoint proteins. At least eight protein kinases are implicated in spindle checkpoint signaling, arguing that a traditional signal transduction cascade is integral to spindle checkpoint signaling.|Animals[MESH]|Cell Cycle Proteins/genetics/*metabolism[MESH]|Cell Cycle/*physiology[MESH]|Genes, cdc[MESH]|Humans[MESH]|Kinetochores/*metabolism[MESH]|Microtubules/*metabolism[MESH]|Models, Biological[MESH]|Protein Binding[MESH]|Protein Kinases/metabolism[MESH]|Signal Transduction/*physiology[MESH]|Spindle Apparatus/*metabolism[MESH] |