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Contrast-induced acute kidney injury McCullough PAJ Am Coll Cardiol 2008[Apr]; 51 (15): 1419-28Cardiac angiography and coronary/vascular interventions depend on iodinated contrast media and consequently pose the risk of contrast-induced acute kidney injury (AKI). This is an important complication that accounts for a significant number of cases of hospital-acquired renal failure, with adverse effects on prognosis and health care costs. The epidemiology and pathogenesis of contrast-induced AKI, baseline renal function measurement, risk assessment, identification of high-risk patients, contrast medium use, and preventive strategies are discussed in this report. An advanced algorithm is suggested for the risk stratification and management of contrast-induced AKI as it relates to patients undergoing cardiovascular procedures. Contrast-induced AKI is likely to remain a significant challenge for cardiologists in the future because the patient population is aging and chronic kidney disease and diabetes are becoming more common.|Acute Kidney Injury/*chemically induced/epidemiology/therapy[MESH]|Biomarkers/blood[MESH]|Contrast Media/*adverse effects[MESH]|Humans[MESH]|Prognosis[MESH]|Renal Dialysis[MESH]|Risk Factors[MESH]|United States/epidemiology[MESH] |
