Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Use of aromatase inhibitors in children and adolescents with disorders of growth and adolescent development Shulman DI; Francis GL; Palmert MR; Eugster EAPediatrics 2008[Apr]; 121 (4): e975-83Although treatment of children and adolescents who have disorders of growth and adolescent development with aromatase inhibitors is increasingly common, data for or against their use are extremely limited. Precocious puberty, short stature, and gynecomastia are conditions for which inhibition of the enzyme aromatase might prove beneficial to reduce clinical signs of estrogenization and/or estrogen-mediated skeletal maturation. In this report, we summarize the published data regarding the use of aromatase inhibitors in these conditions, and review known and potential benefits, safety concerns, and shortcomings of the available information.|Adolescent[MESH]|Age Factors[MESH]|Aromatase Inhibitors/*therapeutic use[MESH]|Body Height/drug effects[MESH]|Bone Density/drug effects[MESH]|Bone Development/drug effects/physiology[MESH]|Child[MESH]|Child Development/drug effects/physiology[MESH]|Child, Preschool[MESH]|Female[MESH]|Growth Disorders/diagnosis/*drug therapy[MESH]|Gynecomastia/*drug therapy[MESH]|Humans[MESH]|Male[MESH]|Prognosis[MESH]|Puberty, Precocious/*drug therapy[MESH]|Risk Assessment[MESH]|Sensitivity and Specificity[MESH]|Sex Factors[MESH]|Sexual Maturation/drug effects/physiology[MESH] |