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MicroRNA-206: the skeletal muscle-specific myomiR McCarthy JJBiochim Biophys Acta 2008[Nov]; 1779 (11): 682-91MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene silencing. A small number of striated muscle-specific miRNAs have been identified and shown to have an important role in myogenesis, embryonic muscle growth and cardiac function and hypertrophy. One of these myomiRs (myo=muscle+miR=miRNA), miR-206, is unique in that it is only expressed in skeletal muscle. The purpose of this review is to discuss what is currently known about miR-206 and its function in myogenesis as well as propose potential new roles for miR-206 in skeletal muscle biology. The review is also intended to serve as a comprehensive resource for miR-206 with the hope of encouraging further research on the role of miR-206 in skeletal muscle.|Animals[MESH]|Base Sequence[MESH]|Humans[MESH]|MicroRNAs/genetics/*metabolism[MESH]|Molecular Sequence Data[MESH]|Muscle Development/genetics[MESH]|Muscle, Skeletal/*metabolism[MESH]|Organ Specificity[MESH] |
