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  • MicroRNA-206: the skeletal muscle-specific myomiR
  • McCarthy JJ
  • Biochim Biophys Acta 2008[Nov]; 1779 (11): 682-91
  • MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene silencing. A small number of striated muscle-specific miRNAs have been identified and shown to have an important role in myogenesis, embryonic muscle growth and cardiac function and hypertrophy. One of these myomiRs (myo=muscle+miR=miRNA), miR-206, is unique in that it is only expressed in skeletal muscle. The purpose of this review is to discuss what is currently known about miR-206 and its function in myogenesis as well as propose potential new roles for miR-206 in skeletal muscle biology. The review is also intended to serve as a comprehensive resource for miR-206 with the hope of encouraging further research on the role of miR-206 in skeletal muscle.
  • |Animals[MESH]
  • |Base Sequence[MESH]
  • |Humans[MESH]
  • |MicroRNAs/genetics/*metabolism[MESH]
  • |Molecular Sequence Data[MESH]
  • |Muscle Development/genetics[MESH]
  • |Muscle, Skeletal/*metabolism[MESH]
  • |Organ Specificity[MESH]

  • *{{pmid18381085}}
    *<b>[ MicroRNA-206: the skeletal muscle-specific myomiR ]</b> Biochim Biophys Acta 2008; 1779(11) ; 682-91 McCarthy JJ


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    Biochim Biophys Acta

    682 11.1779 2008