Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Polarized immune responses differentially regulate cancer development Johansson M; Denardo DG; Coussens LMImmunol Rev 2008[Apr]; 222 (ä): 145-54Tumor-associated immune responses assert varied responses toward developing neoplasms that can either act to eradicate malignant cells via engagement of potent cytotoxic programs or alternatively enhance tumor growth through release of multifunctional pro-tumor mediators. Seemingly paradoxical, these disparate activities reflect a continuum of polarization (or activation) states possible for distinct leukocyte subsets that demonstrate tissue, organ, and tumor selectivity. Herein, we review clinical and experimental studies investigating cellular and molecular mechanisms utilized by neoplastic tissues to alternatively polarize immune responses that favor either pro- or anti-tumor immunity.|*Immunity, Cellular[MESH]|Animals[MESH]|Cell Lineage/immunology[MESH]|Cell Transformation, Neoplastic/*immunology[MESH]|Humans[MESH]|Immunity, Innate[MESH]|Inflammation/immunology[MESH]|Mice[MESH]|Neoplasms/blood supply/*immunology/pathology/therapy[MESH]|Neovascularization, Pathologic[MESH]|Rats[MESH]|Receptors, Fc/immunology[MESH]|Suppressor Factors, Immunologic/immunology[MESH]|T-Lymphocyte Subsets/immunology[MESH]|T-Lymphocytes, Regulatory/immunology[MESH]|Toll-Like Receptors/immunology[MESH] |