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lüll Thyroid function disorders--Guidelines of the Netherlands Association of Internal Medicine Muller AF; Berghout A; Wiersinga WM; Kooy A; Smits JW; Hermus ARNeth J Med 2008[Mar]; 66 (3): 134-42Thyroid function disorders are common with a female to male ratio of 4 to 1. In adult women primary hypothyroidism and thyrotoxicosis have a prevalence of 3.5/1000 and 0.8/1000, respectively. This guideline is aimed at secondary care providers especially internists, but also contains relevant information for interested general practitioners and gynaecologists. A multidisciplinary working group, containing delegates of professional and patient organisations, prepared the guideline. According to principles of 'evidence-based medicine' available literature was studied and discussed. Considering the availability and quality of published studies a practical advice was formulated. For a full overview of the literature and considerations the reader is referred to the original version of the guideline (accessible through NIV-net). In this manuscript we have aimed to provide the practicing internist with practical and 'as evidence-based as possible' treatment guidelines with respect to thyroid function disorders.|*Hyperthyroidism/diagnosis/metabolism/radiotherapy[MESH]|*Hypothyroidism/diagnosis/drug therapy/metabolism[MESH]|Adult[MESH]|Female[MESH]|Graves Disease/diagnosis/metabolism/radiotherapy[MESH]|Humans[MESH]|Iodine Radioisotopes/therapeutic use[MESH]|Male[MESH]|Netherlands[MESH]|Pregnancy[MESH]|Pregnancy Complications/diagnosis/metabolism/therapy[MESH]|Prevalence[MESH]|Severity of Illness Index[MESH]|Thyroid Gland/*metabolism[MESH]|Thyrotoxicosis/diagnosis/metabolism/radiotherapy[MESH]|Thyroxine/therapeutic use[MESH] |