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lüll 8-year follow-up of patients treated for borderline personality disorder: mentalization-based treatment versus treatment as usual Bateman A; Fonagy PAm J Psychiatry 2008[May]; 165 (5): 631-8OBJECTIVE: This study evaluated the effect of mentalization-based treatment by partial hospitalization compared to treatment as usual for borderline personality disorder 8 years after entry into a randomized, controlled trial and 5 years after all mentalization-based treatment was complete. METHOD: Interviewing was by research psychologists blind to original group allocation and structured review of medical notes of 41 patients from the original trial. Multivariate analysis of variance, chi-square, univariate analysis of variance, and nonparametric Mann-Whitney statistics were used to contrast the two groups depending on the distribution of the data. RESULTS: Five years after discharge from mentalization-based treatment, the mentalization-based treatment by partial hospitalization group continued to show clinical and statistical superiority to treatment as usual on suicidality (23% versus 74%), diagnostic status (13% versus 87%), service use (2 years versus 3.5 years of psychiatric outpatient treatment), use of medication (0.02 versus 1.90 years taking three or more medications), global function above 60 (45% versus 10%), and vocational status (employed or in education 3.2 years versus 1.2 years). CONCLUSIONS: Patients with 18 months of mentalization-based treatment by partial hospitalization followed by 18 months of maintenance mentalizing group therapy remain better than those receiving treatment as usual, but their general social function remains impaired.|Adult[MESH]|Borderline Personality Disorder/drug therapy/epidemiology/*therapy[MESH]|Double-Blind Method[MESH]|Drug Therapy/*methods/*statistics & numerical data[MESH]|Female[MESH]|Follow-Up Studies[MESH]|Hospitalization/*statistics & numerical data[MESH]|Humans[MESH]|Psychotherapy/*methods/*statistics & numerical data[MESH]|Suicide, Attempted/psychology[MESH] |