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NKT cells in tumor immunity: opposing subsets define a new immunoregulatory axis Berzofsky JA; Terabe MJ Immunol 2008[Mar]; 180 (6): 3627-35NKT cells are true Ag-specific T cells that also have innate properties and form a bridge between the innate and adaptive immune systems. Distinct NKT cell subsets play positive and negative regulatory roles and define a new immunoregulatory axis with broad implications for tumor immunity and other immunological and disease settings.|*Immunity, Innate/genetics[MESH]|Animals[MESH]|Cell Communication/genetics/*immunology[MESH]|Epitopes, T-Lymphocyte/biosynthesis/genetics/physiology[MESH]|Humans[MESH]|Killer Cells, Natural/*classification/*immunology/metabolism[MESH]|Neoplasms/*immunology/metabolism/pathology[MESH]|T-Lymphocyte Subsets/*classification/*immunology/metabolism[MESH] |
