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lüll Hereditary leiomyomatosis and renal cell carcinoma syndrome: a case report Hayedeh G; Fatemeh M; Ahmadreza R; Masoud A; Ahmad SDermatol Online J 2008[Jan]; 14 (1): 16The simultaneous occurrence of multiple cutaneous leiomyomas, uterine leiomyomatosis, and renal cancer is described as a cancer syndrome with an autosomal dominant pattern of inheritance. We report a 79-year-old man who presented with multiple hyperkeratotic, erythematous nodules on his right leg with a histological diagnosis of pilar leiomyoma. In a review of systems, gross hematuria, weight loss, and bone pain were noted. His pathologic diagnosis was determined to be metastatic papillary renal cell carcinoma. A family history revealed that his sister had a hysterectomy for uterine leiomyomas. The findings in this case can be attributed to hereditary leiomyomatosis and renal cell carcinoma syndrome.|Aged[MESH]|Carcinoma, Renal Cell/*genetics[MESH]|Female[MESH]|Humans[MESH]|Kidney Neoplasms/*genetics[MESH]|Leiomyomatosis/*genetics[MESH]|Male[MESH]|Neoplasms, Multiple Primary/*genetics[MESH]|Siblings[MESH]|Skin Neoplasms/*genetics[MESH]|Uterine Neoplasms/genetics[MESH] |