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Functions of O-fucosyltransferase in Notch trafficking and signaling: towards the end of a controversy?Vodovar N; Schweisguth FJ Biol 2008[]; 7 (2): 7The precise role of the O-fucosyltransferase Ofut1 in Notch-receptor trafficking has remained controversial. A recent study sheds new light on the non-catalytic activity of Ofut1 and provides further evidence that Ofut1 acts as a chaperone in the endoplasmic reticulum.|Animals[MESH]|Fucosyltransferases/*physiology[MESH]|Humans[MESH]|Protein Transport/physiology[MESH]|Receptors, Notch/genetics/*physiology[MESH]|Signal Transduction/*physiology[MESH] |
