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  lüll Epidemiology, clinical manifestations, and treatment options for skin and soft  tissue infection caused by community-acquired methicillin-resistant  Staphylococcus aureus Farley JEJ Am Acad Nurse Pract  2008[Feb]; 20 (2): 85-92PURPOSE: This article reviews the evolving epidemiology of community-acquired  methicillin-resistant Staphylococcus aureus (CA-MRSA) and the appropriate  outpatient management of CA-MRSA skin and soft tissue infection. Further, the  paper will provide the basis upon which an individualized patient educational  plan may be developed. DATA SOURCES: To complete this review, a search of English  language publications was conducted through Medline and CINAHL databases  (1966-2006). CONCLUSIONS: The epidemiology of CA-MRSA is becoming increasingly  complex. Research that addresses the impact of this organism in high-risk  populations and within families is urgently needed. IMPLICATIONS FOR PRACTICE:  Nurse practitioners must remain informed of the epidemiology of common and  emerging drug-resistant organisms in their patient populations.|*Community-Acquired Infections/diagnosis/epidemiology/therapy[MESH]|*Methicillin Resistance[MESH]|*Soft Tissue Infections/diagnosis/epidemiology/therapy[MESH]|*Staphylococcal Skin Infections/diagnosis/epidemiology/therapy[MESH]|*Staphylococcus aureus[MESH]|Communicable Diseases, Emerging/diagnosis/epidemiology/therapy[MESH]|Cross Infection/diagnosis/epidemiology/therapy[MESH]|Humans[MESH]|Microbial Sensitivity Tests[MESH]|Molecular Epidemiology[MESH]|Nurse Practitioners/*organization & administration[MESH]|Nurse's Role[MESH]|Nursing Assessment[MESH]|Risk Factors[MESH] |