Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
free free
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll The contribution of growth hormone to mammary neoplasia Perry JK; Mohankumar KM; Emerald BS; Mertani HC; Lobie PEJ Mammary Gland Biol Neoplasia 2008[Mar]; 13 (1): 131-45While the effects of growth hormone (GH) on longitudinal growth are well established, the observation that GH contributes to neoplastic progression is more recent. Accumulating literature implicates GH-mediated signal transduction in the development and progression of a wide range malignancies including breast cancer. Recently autocrine human GH been demonstrated to be an orthotopically expressed oncogene for the human mammary gland. This review will highlight recent evidence linking GH and mammary carcinoma and discuss GH-antagonism as a potential therapeutic approach for treatment of breast cancer.|Animals[MESH]|Autocrine Communication[MESH]|Breast Neoplasms/drug therapy/*metabolism[MESH]|Cell Transformation, Neoplastic/metabolism[MESH]|Disease Models, Animal[MESH]|Growth Hormone/antagonists & inhibitors/*metabolism[MESH]|Humans[MESH]|Risk Factors[MESH] |