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lüll Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics Tran TD; Caruthers SD; Hughes M; Marsh JN; Cyrus T; Winter PM; Neubauer AM; Wickline SA; Lanza GMInt J Nanomedicine 2007[]; 2 (4): 515-26Molecular imaging is a novel tool that has allowed non-invasive diagnostic imaging to transition from gross anatomical description to identification of specific tissue epitopes and observation of biological processes at the cellular level. This technique has been confined to the field of nuclear imaging; however, recent advances in nanotechnology have extended this research to include ultrasound (US) and magnetic resonance (MR) imaging. The exploitation of nanotechnology for MR and US molecular imaging has generated several candidate contrast agents. One multimodality platform, targeted perfluorocarbon (PFC) nanoparticles, is useful for noninvasive detection with US and MR, targeted drug delivery, and quantification.|Clinical Medicine/trends[MESH]|Contrast Media[MESH]|Diagnostic Imaging/*trends[MESH]|Drug Carriers/chemistry[MESH]|Drug Delivery Systems/*trends[MESH]|Fluorocarbons/*chemistry[MESH]|Molecular Probe Techniques/*trends[MESH]|Nanomedicine/trends[MESH]|Nanoparticles/*therapeutic use[MESH] |