suck pdf from google scholar
unlimited free pdf from europmc18199488    free
PDF from PMC    free
html from PMC    free
PDF vom PMID18199488  :  Publisher
PDF vom PMID18199488
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text


  • DeepDyve
  • Pubget Overpricing


  • lüll
  • IL-24 modulates IFN-gamma expression in patients with tuberculosis
  • Wu B; Huang C; Kato-Maeda M; Hopewell PC; Daley CL; Krensky AM; Clayberger C
  • Immunol Lett 2008[Apr]; 117 (1): 57-62
  • IL-24 is a newly described member of the IL-10 family. We previously demonstrated that PBMC from TB patients exhibited low levels of IL-24 and IFN-gamma compared to subjects with latent tuberculosis infection (LTBI). In order to investigate the role of IL-24 in IFN-gamma expression in TB patients, we stimulated PBMC from individuals with LTBI or TB patients with the Mtb-specific antigen, early secretory antigenic target-6 (ESAT-6) and measured cytokine expression using quantitative real-time PCR (qPCR). Exogenous IL-24 increased IFN-gamma expression in PBMC obtained from TB patients while neutralization of IL-24 reduced IFN-gamma expression in PBMC from subjects with LTBI. Exogenous IL-24 enhanced IFN-gamma expression by increasing expression of IL-12 family cytokines, including IL-12alpha, IL-12beta, IL-23alpha and IL-27, and by reducing FOXP3 expression in PBMC from TB patients. This is the first demonstration that IL-24 may play an important role in IFN-gamma expression following infection with Mtb.
  • |Forkhead Transcription Factors/metabolism[MESH]
  • |Gene Expression/drug effects[MESH]
  • |Humans[MESH]
  • |Interferon-gamma/genetics/*metabolism[MESH]
  • |Interleukins/biosynthesis/metabolism/*pharmacology[MESH]
  • |Leukocytes, Mononuclear/drug effects/immunology[MESH]
  • |RNA, Messenger/metabolism[MESH]
  • |Tuberculosis, Pulmonary/*immunology[MESH]
  • |Up-Regulation[MESH]





  • *{{pmid18199488}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=18199488 IL-24 modulates IFN-gamma expression in patients with tuberculosis ]</b> Immunol Lett 2008; 117(1) ; 57-62 Wu B; Huang C; Kato-Maeda M; Hopewell PC; Daley CL; Krensky AM; Clayberger C

        *18199488*

    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    Immunol Lett

    57 1.117 2008