Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
Warning: file_get_contents(http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=18154526&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 445
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
The spread of CTX-M-type extended-spectrum beta-lactamases Rossolini GM; D'Andrea MM; Mugnaioli CClin Microbiol Infect 2008[Jan]; 14 Suppl 1 (ä): 33-41CTX-M-type enzymes are a group of class A extended-spectrum beta-lactamases (ESBLs) that are rapidly spreading among Enterobacteriaceae worldwide. More that 50 allotypes are known, clustered into six sub-lineages. The CTX-M-encoding genes have been captured from the chromosome of Kluyvera spp. on conjugative plasmids that mediate their dissemination among pathogenic enterobacteria. CTX-M-type ESBLs exhibit powerful activity against cefotaxime and ceftriaxone but generally not against ceftazidime, which has important implications for laboratory detection. However, several CTX-M variants with enhanced ceftazidimase activity have been detected. The rapid and massive spread of CTX-M-type ESBLs is rapidly changing the ESBL epidemiology and, in some geographical areas, these enzymes are now the most prevalent ESBLs in Enterobacteriaceae.|*beta-Lactam Resistance/genetics[MESH]|*beta-Lactamases/chemistry/genetics/metabolism[MESH]|Anti-Bacterial Agents/metabolism/*pharmacology[MESH]|Cefotaxime/metabolism/pharmacology[MESH]|Ceftazidime/metabolism/pharmacology[MESH]|Ceftriaxone/metabolism/pharmacology[MESH]|Cephalosporins/metabolism/*pharmacology[MESH]|Enterobacteriaceae Infections/*epidemiology/microbiology[MESH]|Enterobacteriaceae/drug effects/*enzymology/genetics[MESH]|Humans[MESH]|Models, Molecular[MESH]|Prevalence[MESH] |
