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Mesial temporal sclerosis in children Brandao EM; Manreza MLArq Neuropsiquiatr 2007[Dec]; 65 (4A): 947-50Mesial temporal sclerosis is the most frequent cause of drug-resistant temporal lobe epilepsy but has a satisfactory response to surgery, and is considered infrequent in children. OBJECTIVE: To evaluate the clinical, electrographic and radiological spectrum of the disease in children. METHOD: Retrospective study by review of charts of 44 children with a diagnosis of mesial temporal sclerosis on magnetic resonance imaging, attended at the "Hospital das Clinicas" of the University of Sao Paulo Faculty of Medicine. RESULTS: Febrile seizure was identified in the history of 54% of the patients. Injuries at the left side predominated in patients with schooling difficulties (p=0.049), in those with first seizures between six months and five years (p=0.021) and in those with complex febrile seizure (p=0.032). Thirteen patients were submitted to surgery and of these, eight remained without seizures. CONCLUSION: Febrile seizure may be related in a more direct way to the presence of left-side mesial temporal sclerosis.|Adolescent[MESH]|Child[MESH]|Child, Preschool[MESH]|Electroencephalography[MESH]|Female[MESH]|Humans[MESH]|Magnetic Resonance Imaging[MESH]|Male[MESH]|Retrospective Studies[MESH]|Sclerosis[MESH]|Seizures, Febrile/*etiology[MESH]|Temporal Lobe/*pathology/surgery[MESH] |
