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Primary hyperparathyroidism and familial hyperparathyroid syndromes Blackburn M; Diamond TAust Fam Physician 2007[Dec]; 36 (12): 1029-33BACKGROUND: Ninety percent of cases of hypercalcaemia are due to primary hyperparathyroidism or hypercalcaemia of malignancy. OBJECTIVE: This article outlines the diagnostic features of primary hyperparathyroidism and determines who would benefit from parathyroidectomy. It also aims to raise awareness of familial hyperparathyroid syndromes. DISCUSSION: Diagnosis of primary hyperparathyroidism requires hypercalcaemia, elevated or inappropriately normal serum parathyroid hormone and a fractional urinary excretion of calcium greater than 0.02. Many patients benefit from parathyroidectomy, which has a high rate of cure.|Adult[MESH]|Aged[MESH]|Female[MESH]|Humans[MESH]|Hypercalcemia[MESH]|Hyperparathyroidism[MESH]|Hyperparathyroidism, Primary/*diagnosis/physiopathology/surgery[MESH]|Male[MESH]|Middle Aged[MESH]|Multiple Endocrine Neoplasia Type 1[MESH]|Multiple Endocrine Neoplasia Type 2a[MESH]|Parathyroid Hormone/blood[MESH] |
