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Genetics of atrial fibrillation Ellinor PT; Yi BA; MacRae CAMed Clin North Am 2008[Jan]; 92 (1): 41-51, xRecent studies of atrial fibrillation (AF) have identified mutations in a series of ion mutations; however, these channels appear to be relatively rare causes of AF. Recent genome-wide association studies for AF have identified novel variants associated with the disease, although the mechanism of action for these variants remains unknown. Ultimately, a greater understanding of the genetics of AF should yield insights into novel pathways, therapeutic targets, and diagnostic testing for this common arrhythmia.|Atrial Fibrillation/epidemiology/*genetics[MESH]|Genetic Predisposition to Disease/*genetics[MESH]|Humans[MESH]|Morbidity[MESH]|Phenotype[MESH]|Risk Factors[MESH]|United States/epidemiology[MESH] |
