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Uterine receptivity to human embryonic implantation: histology, biomarkers, and transcriptomics Aghajanova L; Hamilton AE; Giudice LCSemin Cell Dev Biol 2008[Apr]; 19 (2): 204-11Embryonic implantation is a dynamic process of paracrine interactions between the maternal compartment and the conceptus and involves a receptive endometrium and a developmentally competent blastocyst. Herein, we review histology, clinical approaches, and the promise of transcriptomics in elucidating mechanisms underlying implantation and development of biomarkers of uterine receptivity-with an eye to diagnose and treat implantation-based disorders of miscarriage, fetal growth restriction, pre-eclampsia, and infertility.|*Gene Expression Profiling[MESH]|Biomarkers/analysis/metabolism[MESH]|Cells, Cultured[MESH]|Embryo Implantation/*genetics/*physiology[MESH]|Endometrium/physiology[MESH]|Female[MESH]|Humans[MESH]|Menstrual Cycle/physiology[MESH]|Models, Biological[MESH]|Pregnancy[MESH]|Uterus/*anatomy & histology/metabolism/*physiology[MESH] |
