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lüll Role of polysaccharides in Pseudomonas aeruginosa biofilm development Ryder C; Byrd M; Wozniak DJCurr Opin Microbiol 2007[Dec]; 10 (6): 644-8During the past decade, there has been a renewed interest in using Pseudomonas aeruginosa as a model system for biofilm development and pathogenesis. Since the biofilm matrix represents a crucial interface between the bacterium and the host or its environment, considerable effort has been expended to acquire a more complete understanding of the matrix composition. Here, we focus on recent developments regarding the roles of alginate, Psl, and Pel polysaccharides in the biofilm matrix.|*Gene Expression Regulation, Bacterial[MESH]|Alginates/metabolism[MESH]|Bacterial Proteins/genetics/*metabolism[MESH]|Biofilms/*growth & development[MESH]|Extracellular Matrix/metabolism[MESH]|Humans[MESH]|Polysaccharides, Bacterial/*metabolism[MESH]|Pseudomonas aeruginosa/genetics/*growth & development/metabolism[MESH] |