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Scientific basis for the treatment of low back pain Mulholland RCAnn R Coll Surg Engl 2007[Oct]; 89 (7): 677-81Disc degeneration causes back pain because the function of the disc as a load transferring structure is abnormal, producing abnormal patterns of load which cause pain. Fusion has been unpredictable because it only fortuitously addresses loading. A fusion may be in such a position that it takes load from the disc, and this may be reflected in the way the fusion models, demonstrating a weight bearing pattern, but this is unpredictable. Recognition that we are dealing with a problem of load transfer allows us to design any surgical implant to solve this problem, without stopping movement.|*Intervertebral Disc[MESH]|Artificial Organs[MESH]|Humans[MESH]|Low Back Pain/etiology/*therapy[MESH]|Prosthesis Design[MESH]|Spinal Diseases/*complications[MESH]|Spinal Fusion/methods[MESH]|Stress, Mechanical[MESH] |