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lüll Nephrotic proteinuria and the autonomic nervous system Camici MSaudi J Kidney Dis Transpl 2007[Nov]; 18 (4): 512-22Nephrotic proteinuria triggers off complex neuro-endocrine mechanisms where forebrain activation results in sympathetic over activity. An attempt is made to discuss and analyze the renal sympathetic efferent nerve hyperactivity, the role played by the angiotensin/nitric oxide system during proteinuria and the nitric oxide/angiotensin imbalance in the hypothalamus. Several questions arise: further experimental and clinical studies are necessary. The answers to these questions may disclose new clinical and therapeutic perspectives for the nephrotic syndrome.|Autonomic Nervous System Diseases/*etiology/physiopathology[MESH]|Autonomic Nervous System/*physiopathology[MESH]|Disease Progression[MESH]|Glomerular Filtration Rate[MESH]|Humans[MESH]|Kidney/*innervation[MESH]|Prognosis[MESH]|Proteinuria/*complications/physiopathology[MESH] |