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  • Regulatory role of cathepsin D in apoptosis
  • Minarowska A; Minarowski L; Karwowska A; Gacko M
  • Folia Histochem Cytobiol 2007[]; 45 (3): 159-63
  • Cathepsin D (CTSD, EC 3.4.23.5) is well known aspartyl protease. Among different role in cell physiology, a new function of this enzyme is examined. Cathepsin D is an important regulator of apoptotic pathways in cells. It acts at different stage of intrinsic and extrinsic pathway of apoptosis. Cathepsin D can either induce apoptosis in presence of cytotoxic factors, but in certain studies an inhibitory role in apoptosis was also reviewed. Detailed review of involvement of cathepsin D in cell apoptosis is a purpose of this paper.
  • |Animals[MESH]
  • |Apoptosis/*physiology[MESH]
  • |Cathepsin D/*physiology[MESH]
  • |Humans[MESH]





  • *{{pmid17951163}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=17951163 Regulatory role of cathepsin D in apoptosis ]</b> Folia Histochem Cytobiol 2007; 45(3) ; 159-63 Minarowska A; Minarowski L; Karwowska A; Gacko M

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    Folia Histochem Cytobiol

    159 3.45 2007