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Managing the acutely agitated and psychotic patient Nordstrom K; Allen MHCNS Spectr 2007[Oct]; 12 (10 Suppl 17): 5-11Agitation can present as an emergency in the course of numerous psychiatric conditions including intoxication, schizophrenia, bipolar disorder, and delirium. This article reviews relevant literature regarding the definition, etiology, measurement, and management of episodic agitation and pays particular attention to intramuscular treatments. The impact of changes in methodology between the era of first- and second-generation antipsychotics, the implications of those changes for external validity of studies of second-generation studies, and the recent evolution of expert consensus are discussed.|Antipsychotic Agents/therapeutic use[MESH]|Aripiprazole[MESH]|Benzodiazepines/therapeutic use[MESH]|Dibenzothiazepines/therapeutic use[MESH]|Emergencies[MESH]|Humans[MESH]|Olanzapine[MESH]|Piperazines/therapeutic use[MESH]|Psychomotor Agitation/diagnosis/*drug therapy[MESH]|Quetiapine Fumarate[MESH]|Quinolones/therapeutic use[MESH]|Risperidone/therapeutic use[MESH]|Schizophrenia/*drug therapy[MESH]|Thiazoles/therapeutic use[MESH] |