Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
 free
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 free
 free
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
LSD1 and the chemistry of histone demethylation Culhane JC; Cole PACurr Opin Chem Biol 2007[Oct]; 11 (5): 561-8The recent discovery that histone demethylation can be catalyzed by the flavin-dependent amine oxidase LSD1 has ushered in a new chapter in the chromatin-remodeling community. Herein, we discuss the rapid progress of the histone demethylase field including the recent identification of the non-heme iron-dependent histone demethylases (JmjC family), the basis for LSD1 substrate site specificity and the newly emerging potential for inhibition of these enzymes in structural and functional analysis.|*Chromatin Assembly and Disassembly[MESH]|*Protein Processing, Post-Translational[MESH]|Catalysis[MESH]|Enzyme Inhibitors[MESH]|F-Box Proteins[MESH]|Histone Demethylases[MESH]|Histones/*metabolism[MESH]|Humans[MESH]|Jumonji Domain-Containing Histone Demethylases[MESH]|Methylation[MESH]|Oxidoreductases, N-Demethylating/*metabolism[MESH]|Substrate Specificity[MESH] |
