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lüll Micro- and nanofabrication methods in nanotechnological medical and pharmaceutical devices Betancourt T; Brannon-Peppas LInt J Nanomedicine 2006[]; 1 (4): 483-95Micro- and nanofabrication techniques have revolutionized the pharmaceutical and medical fields as they offer the possibility for highly reproducible mass-fabrication of systems with complex geometries and functionalities, including novel drug delivery systems and bionsensors. The principal micro- and nanofabrication techniques are described, including photolithography, soft lithography, film deposition, etching, bonding, molecular self assembly, electrically induced nanopatterning, rapid prototyping, and electron, X-ray, colloidal monolayer, and focused ion beam lithography. Application of these techniques for the fabrication of drug delivery and biosensing systems including injectable, implantable, transdermal, and mucoadhesive devices is described.|Biocompatible Materials/*chemistry[MESH]|Biosensing Techniques/*methods[MESH]|Drug Delivery Systems/*methods[MESH]|Drug Industry/*methods[MESH]|Equipment Design[MESH]|Equipment Failure Analysis[MESH]|Nanostructures/*chemistry/*therapeutic use/ultrastructure[MESH]|Nanotechnology/*methods[MESH] |