Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
Warning: file_get_contents(http://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=17716384&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 445
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
Inhaled adrenergics and anticholinergics in obstructive lung disease: do they enhance mucociliary clearance?Restrepo RDRespir Care 2007[Sep]; 52 (9): 1159-73; discussion 1173-5Pulmonary mucociliary clearance is an essential defense mechanism against bacteria and particulate matter. Mucociliary dysfunction is an important feature of obstructive lung diseases such as chronic obstructive pulmonary disease, asthma, cystic fibrosis, and bronchiectasis. This dysfunction in airway clearance is associated with accelerated loss of lung function in patients with obstructive lung disease. The involvement of the cholinergic and adrenergic neural pathways in the pathophysiology of mucus hypersecretion suggests the potential therapeutic role of bronchodilators as mucoactive agents. Although anticholinergics and adrenergic agonist bronchodilators have been routinely used, alone or in combination, to enhance mucociliary clearance in patients with obstructive lung disease, the existing evidence does not consistently show clinical effectiveness.|Administration, Inhalation[MESH]|Adrenergic Agents/*administration & dosage/therapeutic use[MESH]|Bronchi/drug effects/physiology/*physiopathology[MESH]|Bronchodilator Agents/*administration & dosage/therapeutic use[MESH]|Cholinergic Antagonists/*administration & dosage/therapeutic use[MESH]|Humans[MESH]|Mucociliary Clearance/*drug effects[MESH]|Mucus/drug effects/*metabolism/physiology[MESH]|Pulmonary Disease, Chronic Obstructive/*drug therapy/physiopathology[MESH]|Respiratory Mucosa/drug effects/*metabolism/physiology[MESH] |
